Skip navigation
  • Logo
  • Home
  • Communities
    & Collections
  • Research Outputs
  • Researchers
  • Projects
  • Explore by
    • Research Outputs
    • Researchers
    • Projects
  • Sign on to:
    • My DSpace
    • Receive email
      updates
    • Edit Account details
FFH logo

  1. RePhyChem
  2. Research Outputs
  3. Journal Article
Please use this identifier to cite or link to this item: https://dspace.ffh.bg.ac.rs/handle/123456789/2053
Title: Paracetamol detection in environmental and pharmaceutical samples using multi-walled carbon nanotubes decorated with silver nanoparticles
Authors: Weheabby, Saddam
Wu, Zhenyn
Al-Hamry, Ammar
Pašti, Igor 
Anurag, Adiraju
Dentel, Doreen
Tegenkamp, Christoph
Kanoun, Olfa
Keywords: Electrochemical sensors;Multi-walled carbon nanotubes;Paracetamol;Silver nanoparticles
Issue Date: 1-Oct-2023
Journal: Microchemical Journal
Abstract: 
Paracetamol (PA) treats mild to moderate pain and fever with a high relative safety factor when administered properly. However, PA overuse creates harmful metabolites and serious illnesses. Thus, PA must be continually monitored and measured in environmental, pharmaceutical, and biological samples. In this work, voltammetric sensing of PA using silver nanoparticles (AgNPs) and carboxylated multi-walled carbon nanotubes (AgNPs@HOOC-MWCNT) deposited on screen-printed carbon electrode (SPCE) has been demonstrated. The AgNPs were prepared through a simple reduction method with an average particle size of 46 nm. Both AgNPs and modified electrodes were characterized by ultraviolet–visible spectroscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, scanning electron microscopy, and energy-dispersive X-ray analysis. The electrochemical behaviour of PA over the modified (AgNPs@HOOC-MWCNT@SPCE) was studied using cyclic voltammetry (CV). It has been demonstrated that a relatively small quantity of AgNPs results in a considerable improvement in the active surface area of the modified electrode and an increase in the oxidation current of PA. In addition, a computational study was performed to complement the experimental work. Using square wave voltammetry (SWV) under optimal conditions (pH 7.4 and 25 °C), AgNPs@HOOC-MWCNT@SPCE sensor shows an effective sensing potential with a limit of detection of 0.24 µM in the concentration range of 0.5 to 1000 µM. The reproducibility and repeatability studies and long-term stability for 60 days were illustrated. Ultimately, the practical applications of the proposed method for determining PA in environmental and pharmaceutical samples were demonstrated with satisfactory results.
URI: https://dspace.ffh.bg.ac.rs/handle/123456789/2053
ISSN: 0026265X
DOI: 10.1016/j.microc.2023.109192
Appears in Collections:Journal Article

Show full item record

SCOPUSTM   
Citations

25
checked on Jun 27, 2025

Page view(s)

40
checked on Jul 3, 2025

Google ScholarTM

Check

Altmetric

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


Explore by
  • Communities
    & Collections
  • Research Outputs
  • Researchers
  • Projects
University of Belgrade
Faculty of Physical Chemistry
Studentski trg 12-16
11158 Belgrade 118
PAC 105305
SERBIA
University of Belgrade Faculty of Physical Chemistry