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Title: | Potentiometric determination of famotidine in pharmaceutical dosage forms | Authors: | Petković, J. Minić, Dragica Korićanac, Z. Antić Jovanović, Ankica |
Issue Date: | 1-Jan-1998 | Journal: | Pharmazie | Abstract: | A simple and rapid method for the determination of famotidine is described. Famotidine is titrated with a solution of palladium(II)-chloride in Britton-Robinson buffer (pH = 3.60) using a silver indicator electrode. A stable yellow complex is formed. A significant step of the potential appears when the stoichiometric ratio of palladium(II) to famotidine is 1:1. The method is suitable for the determination of micro quantities (2.5-0.8 mg) of famotidine alone or in pharmaceutical dosage farms with a relative standard deviation of 0.7-2.3%. |
URI: | https://dspace.ffh.bg.ac.rs/handle/123456789/1947 | ISSN: | 0031-7144 |
Appears in Collections: | Journal Article |
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