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Please use this identifier to cite or link to this item: https://dspace.ffh.bg.ac.rs/handle/123456789/518
DC FieldValueLanguage
dc.contributor.authorMilanovic, Žiko B.en_US
dc.contributor.authorMarkovic, Zoran S.en_US
dc.contributor.authorDimić, Dušanen_US
dc.contributor.authorKlisuric, Olivera R.en_US
dc.contributor.authorRadojevic, Ivana D.en_US
dc.contributor.authorŠeklic, Dragana S.en_US
dc.contributor.authorŽivanovic, Marko N.en_US
dc.contributor.authorDimitrić Marković, Jasminaen_US
dc.contributor.authorRadulovic, Milankaen_US
dc.contributor.authorAvdovic, Edina H.en_US
dc.date.accessioned2022-12-15T16:09:23Z-
dc.date.available2022-12-15T16:09:23Z-
dc.date.issued2021-01-01-
dc.identifier.issn1631-0748en
dc.identifier.urihttps://dspace.ffh.bg.ac.rs/handle/123456789/518-
dc.description.abstractIn the present manuscript, three different 4,7-dihydroxycoumarin derivatives were prepared and structurally characterized by crystallographic and spectroscopic techniques in combination with the B3LYP-D3BJ theoretical method. Cytotoxic and antimicrobial activities of investigated compounds were screened against different cell lines and microorganisms. HCT-116 cells were most sensitive to the 3-(1-(2-hydroxyphenyl)amino) ethylidene)-2,4-dioxochroman-7-yl acetate derivative, while the best antimicrobial activity against Bacillus subtilis ATCC 6633 was shown by 3-(1-(2- hydroxyphenyl)amino)ethylidene)-2,4-dioxochroman-7-yl acetate. The molecular docking study for all compounds with important epidermal growth factor receptors (EGFR) was performed. The results indicate that the largest contribution to the binding energy is through conventional hydrogen bonds.en
dc.relation.ispartofComptes Rendus Chimieen
dc.subject4,7-dihydroxycoumarinen
dc.subjectBiological activityen
dc.subjectCoumarin-derived ligandsen
dc.subjectDFT calculationsen
dc.subjectMolecular dockingen
dc.titleSynthesis, structural characterization, biological activity and molecular docking study of 4,7-dihydroxycoumarinmodified by aminophenol derivativesen_US
dc.typeArticleen_US
dc.identifier.doi10.5802/CRCHIM.68-
dc.identifier.scopus2-s2.0-85106670229-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85106670229-
dc.relation.firstpage215en
dc.relation.lastpage232en
dc.relation.issue2en
dc.relation.volume24en
item.fulltextNo Fulltext-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.cerifentitytypePublications-
crisitem.author.orcid0000-0001-8127-5396-
crisitem.author.orcid0000-0003-4796-6251-
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University of Belgrade
Faculty of Physical Chemistry
Studentski trg 12-16
11158 Belgrade 118
PAC 105305
SERBIA
University of Belgrade Faculty of Physical Chemistry